1t65: Difference between revisions

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[[Image:1t65.gif|left|200px]]<br /><applet load="1t65" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1t65.gif|left|200px]]
caption="1t65, resolution 1.66&Aring;" />
 
'''Crystal structure of the androgen receptor ligand binding domain with DHT and a peptide derived form its physiological coactivator GRIP1 NR box 2 bound in a non-helical conformation'''<br />
{{Structure
|PDB= 1t65 |SIZE=350|CAPTION= <scene name='initialview01'>1t65</scene>, resolution 1.66&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=DHT:DIHYDROTESTOSTERONE'>DHT</scene>
|ACTIVITY=
|GENE= AR, NR3C4, DHTR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), NCOA2, TIF2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of the androgen receptor ligand binding domain with DHT and a peptide derived form its physiological coactivator GRIP1 NR box 2 bound in a non-helical conformation'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1T65 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=DHT:'>DHT</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T65 OCA].  
1T65 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T65 OCA].  


==Reference==
==Reference==
The molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor., Estebanez-Perpina E, Moore JM, Mar E, Delgado-Rodrigues E, Nguyen P, Baxter JD, Buehrer BM, Webb P, Fletterick RJ, Guy RK, J Biol Chem. 2005 Mar 4;280(9):8060-8. Epub 2004 Nov 24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15563469 15563469]
The molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor., Estebanez-Perpina E, Moore JM, Mar E, Delgado-Rodrigues E, Nguyen P, Baxter JD, Buehrer BM, Webb P, Fletterick RJ, Guy RK, J Biol Chem. 2005 Mar 4;280(9):8060-8. Epub 2004 Nov 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15563469 15563469]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: androgen receptor ligand binding domain grip1 nr box2 coactivators crystal structure non-helical]]
[[Category: androgen receptor ligand binding domain grip1 nr box2 coactivators crystal structure non-helical]]


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