1t65: Difference between revisions
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[[Image:1t65.gif|left|200px]] | [[Image:1t65.gif|left|200px]] | ||
'''Crystal structure of the androgen receptor ligand binding domain with DHT and a peptide derived form its physiological coactivator GRIP1 NR box 2 bound in a non-helical conformation''' | {{Structure | ||
|PDB= 1t65 |SIZE=350|CAPTION= <scene name='initialview01'>1t65</scene>, resolution 1.66Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=DHT:DIHYDROTESTOSTERONE'>DHT</scene> | |||
|ACTIVITY= | |||
|GENE= AR, NR3C4, DHTR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), NCOA2, TIF2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Crystal structure of the androgen receptor ligand binding domain with DHT and a peptide derived form its physiological coactivator GRIP1 NR box 2 bound in a non-helical conformation''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1T65 is a [ | 1T65 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T65 OCA]. | ||
==Reference== | ==Reference== | ||
The molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor., Estebanez-Perpina E, Moore JM, Mar E, Delgado-Rodrigues E, Nguyen P, Baxter JD, Buehrer BM, Webb P, Fletterick RJ, Guy RK, J Biol Chem. 2005 Mar 4;280(9):8060-8. Epub 2004 Nov 24. PMID:[http:// | The molecular mechanisms of coactivator utilization in ligand-dependent transactivation by the androgen receptor., Estebanez-Perpina E, Moore JM, Mar E, Delgado-Rodrigues E, Nguyen P, Baxter JD, Buehrer BM, Webb P, Fletterick RJ, Guy RK, J Biol Chem. 2005 Mar 4;280(9):8060-8. Epub 2004 Nov 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15563469 15563469] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
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[[Category: androgen receptor ligand binding domain grip1 nr box2 coactivators crystal structure non-helical]] | [[Category: androgen receptor ligand binding domain grip1 nr box2 coactivators crystal structure non-helical]] | ||
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