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[[Image:1ted.jpg|left|200px]]<br /><applet load="1ted" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ted.jpg|left|200px]]
caption="1ted, resolution 2.25&Aring;" />
 
'''Crystal structure of a type III polyketide synthase PKS18 from Mycobacterium tuberculosis'''<br />
{{Structure
|PDB= 1ted |SIZE=350|CAPTION= <scene name='initialview01'>1ted</scene>, resolution 2.25&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MYR:MYRISTIC ACID'>MYR</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Naringenin-chalcone_synthase Naringenin-chalcone synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.74 2.3.1.74]
|GENE= pks18 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])
}}
 
'''Crystal structure of a type III polyketide synthase PKS18 from Mycobacterium tuberculosis'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1TED is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with <scene name='pdbligand=MYR:'>MYR</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Naringenin-chalcone_synthase Naringenin-chalcone synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.74 2.3.1.74] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TED OCA].  
1TED is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TED OCA].  


==Reference==
==Reference==
A novel tunnel in mycobacterial type III polyketide synthase reveals the structural basis for generating diverse metabolites., Sankaranarayanan R, Saxena P, Marathe UB, Gokhale RS, Shanmugam VM, Rukmini R, Nat Struct Mol Biol. 2004 Sep;11(9):894-900. Epub 2004 Aug 1. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15286723 15286723]
A novel tunnel in mycobacterial type III polyketide synthase reveals the structural basis for generating diverse metabolites., Sankaranarayanan R, Saxena P, Marathe UB, Gokhale RS, Shanmugam VM, Rukmini R, Nat Struct Mol Biol. 2004 Sep;11(9):894-900. Epub 2004 Aug 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15286723 15286723]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Naringenin-chalcone synthase]]
[[Category: Naringenin-chalcone synthase]]
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[[Category: thiolase fold]]
[[Category: thiolase fold]]


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