1tnb: Difference between revisions

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[[Image:1tnb.gif|left|200px]]<br /><applet load="1tnb" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1tnb.gif|left|200px]]
caption="1tnb, resolution 2.85&Aring;" />
 
'''Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a substrate KKSKTKCVIF Peptide Derived from TC21'''<br />
{{Structure
|PDB= 1tnb |SIZE=350|CAPTION= <scene name='initialview01'>1tnb</scene>, resolution 2.85&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene> and <scene name='pdbligand=MGM:2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE'>MGM</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Protein_geranylgeranyltransferase_type_I Protein geranylgeranyltransferase type I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.59 2.5.1.59]
|GENE= FNTA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus]), PGGT1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])
}}
 
'''Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a substrate KKSKTKCVIF Peptide Derived from TC21'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1TNB is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=MES:'>MES</scene> and <scene name='pdbligand=MGM:'>MGM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Protein_geranylgeranyltransferase_type_I Protein geranylgeranyltransferase type I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.59 2.5.1.59] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TNB OCA].  
1TNB is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TNB OCA].  


==Reference==
==Reference==
Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity., Reid TS, Terry KL, Casey PJ, Beese LS, J Mol Biol. 2004 Oct 15;343(2):417-33. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15451670 15451670]
Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity., Reid TS, Terry KL, Casey PJ, Beese LS, J Mol Biol. 2004 Oct 15;343(2):417-33. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15451670 15451670]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Protein geranylgeranyltransferase type I]]
[[Category: Protein geranylgeranyltransferase type I]]
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[[Category: tc21]]
[[Category: tc21]]


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