1c8p: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1c8p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1d4q 1d4q]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C8P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1C8P FirstGlance]. <br> | <table><tr><td colspan='2'>[[1c8p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1d4q 1d4q]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C8P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1C8P FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1c8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c8p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1c8p RCSB], [http://www.ebi.ac.uk/pdbsum/1c8p PDBsum]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1c8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c8p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1c8p RCSB], [http://www.ebi.ac.uk/pdbsum/1c8p PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/IL3RB_HUMAN IL3RB_HUMAN]] Defects in CSF2RB are the cause of pulmonary surfactant metabolism dysfunction type 5 (SMDP5) [MIM:[http://omim.org/entry/614370 614370]]. SMDP5 is a rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.<ref>PMID:21075760</ref> | [[http://www.uniprot.org/uniprot/IL3RB_HUMAN IL3RB_HUMAN]] Defects in CSF2RB are the cause of pulmonary surfactant metabolism dysfunction type 5 (SMDP5) [MIM:[http://omim.org/entry/614370 614370]]. SMDP5 is a rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.<ref>PMID:21075760</ref> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Andrea, R J.D | [[Category: Andrea, R J.D]] | ||
[[Category: Bagley, C J | [[Category: Bagley, C J]] | ||
[[Category: Booker, G W | [[Category: Booker, G W]] | ||
[[Category: Gaunt, C | [[Category: Gaunt, C]] | ||
[[Category: Lopez, A F | [[Category: Lopez, A F]] | ||
[[Category: Mulhern, T D | [[Category: Mulhern, T D]] | ||
[[Category: Vadas, M A | [[Category: Vadas, M A]] | ||
[[Category: Vandeleur, L | [[Category: Vandeleur, L]] | ||
[[Category: Beta sandwich]] | [[Category: Beta sandwich]] | ||
[[Category: Cytokine receptor]] | [[Category: Cytokine receptor]] | ||
[[Category: Fn3 domain]] | [[Category: Fn3 domain]] | ||
[[Category: Membrane protein]] | [[Category: Membrane protein]] | ||
