1tp0: Difference between revisions
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[[Image:1tp0.gif|left|200px]] | [[Image:1tp0.gif|left|200px]] | ||
'''Triple mutation in interleukin 1 beta cavity:replacement of phenylalanines with tryptophan.''' | {{Structure | ||
|PDB= 1tp0 |SIZE=350|CAPTION= <scene name='initialview01'>1tp0</scene>, resolution 2.2Å | |||
|SITE= | |||
|LIGAND= | |||
|ACTIVITY= | |||
|GENE= IL1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Triple mutation in interleukin 1 beta cavity:replacement of phenylalanines with tryptophan.''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1TP0 is a [ | 1TP0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TP0 OCA]. | ||
==Reference== | ==Reference== | ||
Structural and energetic consequences of mutations in a solvated hydrophobic cavity., Adamek DH, Guerrero L, Blaber M, Caspar DL, J Mol Biol. 2005 Feb 11;346(1):307-18. Epub 2004 Dec 24. PMID:[http:// | Structural and energetic consequences of mutations in a solvated hydrophobic cavity., Adamek DH, Guerrero L, Blaber M, Caspar DL, J Mol Biol. 2005 Feb 11;346(1):307-18. Epub 2004 Dec 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15663946 15663946] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: hydrophobicity]] | [[Category: hydrophobicity]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:21:21 2008'' | ||
