1tw5: Difference between revisions

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[[Image:1tw5.gif|left|200px]]<br /><applet load="1tw5" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1tw5.gif|left|200px]]
caption="1tw5, resolution 2.30&Aring;" />
 
'''beta1,4-galactosyltransferase mutant M344H-Gal-T1 in complex with Chitobiose'''<br />
{{Structure
|PDB= 1tw5 |SIZE=350|CAPTION= <scene name='initialview01'>1tw5</scene>, resolution 2.30&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CBS:DI(N-ACETYL-D-GLUCOSAMINE)'>CBS</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UDH:6-AMINOHEXYL-URIDINE-C1,5'-DIPHOSPHATE'>UDH</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene> and <scene name='pdbligand=DIO:1,4-DIETHYLENE DIOXIDE'>DIO</scene>
|ACTIVITY=
|GENE= B4GALT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 Bos taurus])
}}
 
'''beta1,4-galactosyltransferase mutant M344H-Gal-T1 in complex with Chitobiose'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1TW5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=CBS:'>CBS</scene>, <scene name='pdbligand=MN:'>MN</scene>, <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=UDH:'>UDH</scene>, <scene name='pdbligand=MES:'>MES</scene> and <scene name='pdbligand=DIO:'>DIO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TW5 OCA].  
1TW5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TW5 OCA].  


==Reference==
==Reference==
Effect of the Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: crystal structure of the Met344His mutant in complex with chitobiose., Ramakrishnan B, Boeggeman E, Qasba PK, Biochemistry. 2004 Oct 5;43(39):12513-22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15449940 15449940]
Effect of the Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: crystal structure of the Met344His mutant in complex with chitobiose., Ramakrishnan B, Boeggeman E, Qasba PK, Biochemistry. 2004 Oct 5;43(39):12513-22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15449940 15449940]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: met344his mutation; closed conformation; chitobiose binding]]
[[Category: met344his mutation; closed conformation; chitobiose binding]]


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