1umb: Difference between revisions

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[[Image:1umb.gif|left|200px]]<br /><applet load="1umb" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1umb.gif|left|200px]]
caption="1umb, resolution 2.10&Aring;" />
 
'''branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8 in holo-form'''<br />
{{Structure
|PDB= 1umb |SIZE=350|CAPTION= <scene name='initialview01'>1umb</scene>, resolution 2.10&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=TDP:THIAMIN DIPHOSPHATE'>TDP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/3-methyl-2-oxobutanoate_dehydrogenase_(2-methylpropanoyl-transferring) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.4.4 1.2.4.4]
|GENE=
}}
 
'''branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8 in holo-form'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1UMB is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=TDP:'>TDP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/3-methyl-2-oxobutanoate_dehydrogenase_(2-methylpropanoyl-transferring) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.4.4 1.2.4.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UMB OCA].  
1UMB is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UMB OCA].  


==Reference==
==Reference==
Ligand-induced conformational changes and a reaction intermediate in branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8, as revealed by X-ray crystallography., Nakai T, Nakagawa N, Maoka N, Masui R, Kuramitsu S, Kamiya N, J Mol Biol. 2004 Apr 2;337(4):1011-33. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15033367 15033367]
Ligand-induced conformational changes and a reaction intermediate in branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8, as revealed by X-ray crystallography., Nakai T, Nakagawa N, Maoka N, Masui R, Kuramitsu S, Kamiya N, J Mol Biol. 2004 Apr 2;337(4):1011-33. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15033367 15033367]
[[Category: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]]
[[Category: 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: riken structural genomics/proteomics initiative]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: rsgi]]
[[Category: structural genomics]]
[[Category: structural genomic]]


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