1v48: Difference between revisions

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[[Image:1v48.gif|left|200px]]<br /><applet load="1v48" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1v48.gif|left|200px]]
caption="1v48, resolution 2.2&Aring;" />
 
'''Calf spleen purine nucleoside phosphorylase (PNP) binary complex with 9-(5,5-difluoro-5-phosphonopenthyl)guanine'''<br />
{{Structure
|PDB= 1v48 |SIZE=350|CAPTION= <scene name='initialview01'>1v48</scene>, resolution 2.2&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=HA1:9-(5,5-DIFLUORO-5-PHOSPHONOPENTYL)GUANINE'>HA1</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1]
|GENE=
}}
 
'''Calf spleen purine nucleoside phosphorylase (PNP) binary complex with 9-(5,5-difluoro-5-phosphonopenthyl)guanine'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1V48 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=HA1:'>HA1</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V48 OCA].  
1V48 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V48 OCA].  


==Reference==
==Reference==
Calf spleen purine-nucleoside phosphorylase: crystal structure of the binary complex with a potent multisubstrate analogue inhibitor., Luic M, Koellner G, Yokomatsu T, Shibuya S, Bzowska A, Acta Crystallogr D Biol Crystallogr. 2004 Aug;60(Pt 8):1417-24. Epub 2004, Jul 21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15272165 15272165]
Calf spleen purine-nucleoside phosphorylase: crystal structure of the binary complex with a potent multisubstrate analogue inhibitor., Luic M, Koellner G, Yokomatsu T, Shibuya S, Bzowska A, Acta Crystallogr D Biol Crystallogr. 2004 Aug;60(Pt 8):1417-24. Epub 2004, Jul 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15272165 15272165]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Purine-nucleoside phosphorylase]]
[[Category: Purine-nucleoside phosphorylase]]
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[[Category: x-ray crystallography]]
[[Category: x-ray crystallography]]


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