1d4u: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1d4u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D4U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1D4U FirstGlance]. <br> | <table><tr><td colspan='2'>[[1d4u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D4U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1D4U FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d4u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1d4u RCSB], [http://www.ebi.ac.uk/pdbsum/1d4u PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d4u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1d4u RCSB], [http://www.ebi.ac.uk/pdbsum/1d4u PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/XPA_HUMAN XPA_HUMAN]] Defects in XPA are a cause of xeroderma pigmentosum complementation group A (XP-A) [MIM:[http://omim.org/entry/278700 278700]]; also known as xeroderma pigmentosum type 1 (XP1). XP-A is a rare human autosomal recessive disease characterized by solar sensitivity, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities. Group A patients show the most severe skin symptoms and progressive neurological disorders.<ref>PMID:1339397</ref> <ref>PMID:1372103</ref> <ref>PMID:9671271</ref> | [[http://www.uniprot.org/uniprot/XPA_HUMAN XPA_HUMAN]] Defects in XPA are a cause of xeroderma pigmentosum complementation group A (XP-A) [MIM:[http://omim.org/entry/278700 278700]]; also known as xeroderma pigmentosum type 1 (XP1). XP-A is a rare human autosomal recessive disease characterized by solar sensitivity, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities. Group A patients show the most severe skin symptoms and progressive neurological disorders.<ref>PMID:1339397</ref> <ref>PMID:1372103</ref> <ref>PMID:9671271</ref> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Buchko, G W | [[Category: Buchko, G W]] | ||
[[Category: Daughdrill, G W | [[Category: Daughdrill, G W]] | ||
[[Category: Gochin, M | [[Category: Gochin, M]] | ||
[[Category: Isern, N G | [[Category: Isern, N G]] | ||
[[Category: Kennedy, M A | [[Category: Kennedy, M A]] | ||
[[Category: Lingbeck, J | [[Category: Lingbeck, J]] | ||
[[Category: Lorimier, R de | [[Category: Lorimier, R de]] | ||
[[Category: Lowry, D F | [[Category: Lowry, D F]] | ||
[[Category: Rao, S | [[Category: Rao, S]] | ||
[[Category: Spicer, L D | [[Category: Spicer, L D]] | ||
[[Category: Taylor, J | [[Category: Taylor, J]] | ||
[[Category: Wold, M S | [[Category: Wold, M S]] | ||
[[Category: Dna binding protein]] | [[Category: Dna binding protein]] | ||
[[Category: Dna repair]] | [[Category: Dna repair]] | ||
[[Category: Loop-rich domain]] | [[Category: Loop-rich domain]] | ||
[[Category: Nmr relaxation]] | [[Category: Nmr relaxation]] | ||
