1e7v: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1e7v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E7V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1E7V FirstGlance]. <br> | <table><tr><td colspan='2'>[[1e7v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E7V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1E7V FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LY2:2-MORPHOLIN-4-YL-7-PHENYL-4H-CHROMEN-4-ONE'>LY2</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LY2:2-MORPHOLIN-4-YL-7-PHENYL-4H-CHROMEN-4-ONE'>LY2</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">P120S144C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 Sus scrofa])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">P120S144C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 Sus scrofa])</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidylinositol_3-kinase Phosphatidylinositol 3-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.137 2.7.1.137] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphatidylinositol_3-kinase Phosphatidylinositol 3-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.137 2.7.1.137] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e7v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1e7v RCSB], [http://www.ebi.ac.uk/pdbsum/1e7v PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1e7v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e7v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1e7v RCSB], [http://www.ebi.ac.uk/pdbsum/1e7v PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Phosphatidylinositol 3-kinase]] | [[Category: Phosphatidylinositol 3-kinase]] | ||
[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
[[Category: Hawkins, P T | [[Category: Hawkins, P T]] | ||
[[Category: Pacold, M E | [[Category: Pacold, M E]] | ||
[[Category: Perisic, O | [[Category: Perisic, O]] | ||
[[Category: Stephens, L | [[Category: Stephens, L]] | ||
[[Category: Walker, E H | [[Category: Walker, E H]] | ||
[[Category: Williams, R L | [[Category: Williams, R L]] | ||
[[Category: Wymann, M P | [[Category: Wymann, M P]] | ||
[[Category: Ly294002]] | [[Category: Ly294002]] | ||
[[Category: Pi 3k]] | [[Category: Pi 3k]] | ||
[[Category: Secondary messenger generation pi3k]] | [[Category: Secondary messenger generation pi3k]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 23:57, 22 December 2014
Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine
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