1vj5: Difference between revisions

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[[Image:1vj5.gif|left|200px]]<br /><applet load="1vj5" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1vj5.gif|left|200px]]
caption="1vj5, resolution 2.35&Aring;" />
 
'''Human soluble Epoxide Hydrolase- N-cyclohexyl-N'-(4-iodophenyl)urea complex'''<br />
{{Structure
|PDB= 1vj5 |SIZE=350|CAPTION= <scene name='initialview01'>1vj5</scene>, resolution 2.35&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene> and <scene name='pdbligand=CIU:N-CYCLOHEXYL-N'-(4-IODOPHENYL)UREA'>CIU</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Microsomal_epoxide_hydrolase Microsomal epoxide hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.3.2.9 3.3.2.9]
|GENE= EPHX2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Human soluble Epoxide Hydrolase- N-cyclohexyl-N'-(4-iodophenyl)urea complex'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1VJ5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=P6G:'>P6G</scene> and <scene name='pdbligand=CIU:'>CIU</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Microsomal_epoxide_hydrolase Microsomal epoxide hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.3.2.9 3.3.2.9] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VJ5 OCA].  
1VJ5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VJ5 OCA].  


==Reference==
==Reference==
Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis., Gomez GA, Morisseau C, Hammock BD, Christianson DW, Biochemistry. 2004 Apr 27;43(16):4716-23. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15096040 15096040]
Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis., Gomez GA, Morisseau C, Hammock BD, Christianson DW, Biochemistry. 2004 Apr 27;43(16):4716-23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15096040 15096040]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Microsomal epoxide hydrolase]]
[[Category: Microsomal epoxide hydrolase]]
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[[Category: domain-swapped dimer]]
[[Category: domain-swapped dimer]]


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