1oro: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1oro]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ORO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ORO FirstGlance]. <br>
<table><tr><td colspan='2'>[[1oro]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ORO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ORO FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1oro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oro OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1oro RCSB], [http://www.ebi.ac.uk/pdbsum/1oro PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1oro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oro OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1oro RCSB], [http://www.ebi.ac.uk/pdbsum/1oro PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/PYRE_ECOLI PYRE_ECOLI]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity).<ref>PMID:8620002</ref> 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Aghajari, N.]]
[[Category: Aghajari, N]]
[[Category: Gajhede, M.]]
[[Category: Gajhede, M]]
[[Category: Henriksen, A.]]
[[Category: Henriksen, A]]
[[Category: Jensen, K F.]]
[[Category: Jensen, K F]]
[[Category: Inhibitor-enzyme complex]]
[[Category: Inhibitor-enzyme complex]]
[[Category: Phosphoribosyltransferase]]
[[Category: Phosphoribosyltransferase]]
[[Category: Pyrimidine nucleotide biosynthesis]]
[[Category: Pyrimidine nucleotide biosynthesis]]