2xz1: Difference between revisions
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<StructureSection load='2xz1' size='340' side='right' caption='[[2xz1]], [[Resolution|resolution]] 3.35Å' scene=''> | <StructureSection load='2xz1' size='340' side='right' caption='[[2xz1]], [[Resolution|resolution]] 3.35Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2xz1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ricinus_communis Ricinus communis] and [http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XZ1 OCA]. <br> | <table><tr><td colspan='2'>[[2xz1]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ricinus_communis Ricinus communis] and [http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XZ1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XZ1 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=PNY:(2R)-2,4-DIHYDROXY-3,3-DIMETHYL-N-{3-OXO-3-[(2-SULFANYLETHYL)AMINO]PROPYL}BUTANAMIDE'>PNY</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=PNY:(2R)-2,4-DIHYDROXY-3,3-DIMETHYL-N-{3-OXO-3-[(2-SULFANYLETHYL)AMINO]PROPYL}BUTANAMIDE'>PNY</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1oq9|1oq9]], [[1oqb|1oqb]], [[1oq4|1oq4]], [[1oq7|1oq7]], [[2j2f|2j2f]], [[1afr|1afr]], [[2xz0|2xz0]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1oq9|1oq9]], [[1oqb|1oqb]], [[1oq4|1oq4]], [[1oq7|1oq7]], [[2j2f|2j2f]], [[1afr|1afr]], [[2xz0|2xz0]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acyl-[acyl-carrier-protein]_desaturase Acyl-[acyl-carrier-protein] desaturase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.19.2 1.14.19.2] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xz1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xz1 RCSB], [http://www.ebi.ac.uk/pdbsum/2xz1 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xz1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xz1 RCSB], [http://www.ebi.ac.uk/pdbsum/2xz1 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/STAD_RICCO STAD_RICCO]] Converts stearoyl-ACP to oleoyl-ACP by introduction of a cis double bond between carbons Delta(9) and Delta(10) of the acyl chain. [[http://www.uniprot.org/uniprot/ACP1_SPIOL ACP1_SPIOL]] Carrier of the growing fatty acid chain in fatty acid biosynthesis.[HAMAP-Rule:MF_01217] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Remote control of regioselectivity in acyl-acyl carrier protein-desaturases.,Guy JE, Whittle E, Moche M, Lengqvist J, Lindqvist Y, Shanklin J Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16594-9. Epub 2011 Sep 19. PMID:21930947<ref>PMID:21930947</ref> | Remote control of regioselectivity in acyl-acyl carrier protein-desaturases.,Guy JE, Whittle E, Moche M, Lengqvist J, Lindqvist Y, Shanklin J Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16594-9. Epub 2011 Sep 19. PMID:21930947<ref>PMID:21930947</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
== References == | == References == | ||
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[[Category: Ricinus communis]] | [[Category: Ricinus communis]] | ||
[[Category: Spinacia oleracea]] | [[Category: Spinacia oleracea]] | ||
[[Category: Guy, J E | [[Category: Guy, J E]] | ||
[[Category: Lengqvist, J | [[Category: Lengqvist, J]] | ||
[[Category: Lindqvist, Y | [[Category: Lindqvist, Y]] | ||
[[Category: Moche, M | [[Category: Moche, M]] | ||
[[Category: Shanklin, J | [[Category: Shanklin, J]] | ||
[[Category: Whittle, E | [[Category: Whittle, E]] | ||
[[Category: Oxidoreductase-lipid binding protein complex]] | [[Category: Oxidoreductase-lipid binding protein complex]] | ||
