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{{STRUCTURE_3lg8|  PDB=3lg8  |  SCENE=  }}
==Crystal structure of the C-terminal part of subunit E (E101-206) from Methanocaldococcus jannaschii of A1AO ATP synthase==
===Crystal structure of the C-terminal part of subunit E (E101-206) from Methanocaldococcus jannaschii of A1AO ATP synthase===
<StructureSection load='3lg8' size='340' side='right' caption='[[3lg8]], [[Resolution|resolution]] 4.10&Aring;' scene=''>
{{ABSTRACT_PUBMED_20571891}}
== Structural highlights ==
<table><tr><td colspan='2'>[[3lg8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LG8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LG8 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2dm9|2dm9]], [[2dma|2dma]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">atpE, MJ0220 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 ATCC 43067])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lg8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lg8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lg8 RCSB], [http://www.ebi.ac.uk/pdbsum/3lg8 PDBsum]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/VATE_METJA VATE_METJA]] Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lg/3lg8_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The structure of the C-terminus of subunit E (E(101-206)) of Methanocaldococcus jannaschii A-ATP synthase was determined at 4.1 A. E(101-206) consist of a N-terminal globular domain with three alpha-helices and four antiparallel beta-strands and an alpha-helix at the very C-terminus. Comparison of M. jannaschii E(101-206) with the C-terminus E(81-198) subunit E from Pyrococcus horikoshii OT3 revealed that the kink in the C-terminal alpha-helix of E(81-198), involved in dimer formation, is absent in M. jannaschii E(101-206). Whereas a major dimeric surface interface is present between the P. horikoshii E(81-198) molecules in the asymmetric unit, no such interaction could be found in the M. jannaschii E(101-206) molecules. To verify the oligomeric behaviour, the low resolution structure of the recombinant E(85-206) from M. jannaschii was determined using small angle X-ray scattering. Rigid body modeling of two copies of one of the monomer established a fit with a tail to tail arrangement.


==Function==
Crystal and solution structure of the C-terminal part of the Methanocaldococcus jannaschii A(1)A (O) ATP synthase subunit E revealed by X-ray diffraction and small-angle X-ray scattering.,Balakrishna AM, Manimekalai MS, Hunke C, Gayen S, Rossle M, Jeyakanthan J, Gruber G J Bioenerg Biomembr. 2010 Jun 23. PMID:20571891<ref>PMID:20571891</ref>
[[http://www.uniprot.org/uniprot/VATE_METJA VATE_METJA]] Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity).  


==About this Structure==
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
[[3lg8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LG8 OCA].
</div>


==See Also==
==See Also==
*[[ATP synthase|ATP synthase]]
*[[ATPase|ATPase]]
*[[ATPase|ATPase]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:020571891</ref><references group="xtra"/><references/>
__TOC__
</StructureSection>
[[Category: Atcc 43067]]
[[Category: Atcc 43067]]
[[Category: Balakrishna, A M.]]
[[Category: Balakrishna, A M]]
[[Category: Gayen, S.]]
[[Category: Gayen, S]]
[[Category: Gruber, G.]]
[[Category: Gruber, G]]
[[Category: Hunke, C.]]
[[Category: Hunke, C]]
[[Category: Jeyakanthan, J.]]
[[Category: Jeyakanthan, J]]
[[Category: Manimekalai, M S.S.]]
[[Category: Manimekalai, M S.S]]
[[Category: Archaea]]
[[Category: Archaea]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
Retrieved from "https://proteopedia.org/3lg8"