1w2k: Difference between revisions

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[[Image:1w2k.gif|left|200px]]<br /><applet load="1w2k" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1w2k.gif|left|200px]]
caption="1w2k, resolution 3.00&Aring;" />
 
'''TF7A_4380 COMPLEX'''<br />
{{Structure
|PDB= 1w2k |SIZE=350|CAPTION= <scene name='initialview01'>1w2k</scene>, resolution 3.00&Aring;
|SITE= <scene name='pdbsite=AC1:Bgc+Binding+Site+For+Chain+L'>AC1</scene>
|LIGAND= <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene> and <scene name='pdbligand=380:(2R)-2-({4-[AMINO(IMINO)METHYL]PHENYL}AMINO)-N-BENZYL-2-(3,4-DIMETHOXYPHENYL)ACETAMIDE'>380</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Coagulation_factor_VIIa Coagulation factor VIIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.21 3.4.21.21]
|GENE=
}}
 
'''TF7A_4380 COMPLEX'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1W2K is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=FUC:'>FUC</scene>, <scene name='pdbligand=BGC:'>BGC</scene>, <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=CAC:'>CAC</scene> and <scene name='pdbligand=380:'>380</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Coagulation_factor_VIIa Coagulation factor VIIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.21 3.4.21.21] Known structural/functional Site: <scene name='pdbsite=AC1:Bgc+Binding+Site+For+Chain+L'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W2K OCA].  
1W2K is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W2K OCA].  


==Reference==
==Reference==
Design of selective phenylglycine amide tissue factor/factor VIIa inhibitors., Groebke Zbinden K, Banner DW, Ackermann J, D'Arcy A, Kirchhofer D, Ji YH, Tschopp TB, Wallbaum S, Weber L, Bioorg Med Chem Lett. 2005 Feb 1;15(3):817-22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15664864 15664864]
Design of selective phenylglycine amide tissue factor/factor VIIa inhibitors., Groebke Zbinden K, Banner DW, Ackermann J, D'Arcy A, Kirchhofer D, Ji YH, Tschopp TB, Wallbaum S, Weber L, Bioorg Med Chem Lett. 2005 Feb 1;15(3):817-22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15664864 15664864]
[[Category: Coagulation factor VIIa]]
[[Category: Coagulation factor VIIa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: vitamin k]]
[[Category: vitamin k]]


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