1w2n: Difference between revisions

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[[Image:1w2n.gif|left|200px]]<br /><applet load="1w2n" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1w2n.gif|left|200px]]
caption="1w2n, resolution 2.70&Aring;" />
 
'''DEACETOXYCEPHALOSPORIN C SYNTHASE (WITH A N-TERMINAL HIS-TAG) IN COMPLEX WITH FE(II) AND AMPICILLIN'''<br />
{{Structure
|PDB= 1w2n |SIZE=350|CAPTION= <scene name='initialview01'>1w2n</scene>, resolution 2.70&Aring;
|SITE= <scene name='pdbsite=AC1:Pn1+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene> and <scene name='pdbligand=PN1:(2S,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID'>PN1</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.10.1 1.14.10.1]
|GENE=
}}
 
'''DEACETOXYCEPHALOSPORIN C SYNTHASE (WITH A N-TERMINAL HIS-TAG) IN COMPLEX WITH FE(II) AND AMPICILLIN'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1W2N is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus] with <scene name='pdbligand=FE:'>FE</scene> and <scene name='pdbligand=PN1:'>PN1</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Oxidoreductase Oxidoreductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.10.1 1.14.10.1] Known structural/functional Site: <scene name='pdbsite=AC1:Pn1+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W2N OCA].  
1W2N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_clavuligerus Streptomyces clavuligerus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W2N OCA].  


==Reference==
==Reference==
Conformational flexibility of the C terminus with implications for substrate binding and catalysis revealed in a new crystal form of deacetoxycephalosporin C synthase., Oster LM, van Scheltinga AC, Valegard K, Hose AM, Dubus A, Hajdu J, Andersson I, J Mol Biol. 2004 Oct 8;343(1):157-71. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15381427 15381427]
Conformational flexibility of the C terminus with implications for substrate binding and catalysis revealed in a new crystal form of deacetoxycephalosporin C synthase., Oster LM, van Scheltinga AC, Valegard K, Hose AM, Dubus A, Hajdu J, Andersson I, J Mol Biol. 2004 Oct 8;343(1):157-71. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15381427 15381427]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: FE]]
[[Category: FE]]
[[Category: PN1]]
[[Category: PN1]]
[[Category: 2-oxoglutarate dependent oxygenases]]
[[Category: 2-oxoglutarate dependent oxygenase]]
[[Category: antibiotic biosynthesis]]
[[Category: antibiotic biosynthesis]]
[[Category: cephalosporin]]
[[Category: cephalosporin]]
[[Category: mononuclear ferrous enzymes]]
[[Category: mononuclear ferrous enzyme]]
[[Category: oxidoreductase]]
[[Category: oxidoreductase]]
[[Category: penicillin]]
[[Category: penicillin]]


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