4oe7: Difference between revisions
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''' | ==Crystal structure of YagE, a KDG aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal== | ||
<StructureSection load='4oe7' size='340' side='right' caption='[[4oe7]], [[Resolution|resolution]] 1.99Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4oe7]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OE7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OE7 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GXP:(4S)-4-HYDROXY-2,5-DIOXOPENTANOIC+ACID'>GXP</scene>, <scene name='pdbligand=GXS:(4R)-4-HYDROXY-2,5-DIOXOPENTANOIC+ACID'>GXS</scene>, <scene name='pdbligand=GXT:ETHANEDIAL'>GXT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2v8z|2v8z]], [[3n2x|3n2x]], [[3nev|3nev]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oe7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oe7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4oe7 RCSB], [http://www.ebi.ac.uk/pdbsum/4oe7 PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/YAGE_ECOLI YAGE_ECOLI]] Catalyzes the formation of 2-keto-3-deoxy-galactonate (KDGal) from pyruvate and glyceraldehyde. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Baskar, V]] | |||
[[Category: Krishnaswamy, S]] | |||
[[Category: Kumar, P Manoj]] | |||
[[Category: Manicka, S]] | |||
[[Category: Aldolase type i]] | |||
[[Category: Lyase]] | |||
[[Category: Metal coordination]] | |||
[[Category: Schiff base]] | |||
[[Category: Sugar binding]] | |||
[[Category: Tim barrel]] | |||
Revision as of 10:55, 24 December 2014
Crystal structure of YagE, a KDG aldolase protein, in complex with aldol condensed product of pyruvate and glyoxal
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