1wma: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
Line 1: Line 1:
[[Image:1wma.gif|left|200px]]<br /><applet load="1wma" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1wma.gif|left|200px]]
caption="1wma, resolution 1.24&Aring;" />
 
'''Crystal structure of human CBR1 in complex with Hydroxy-PP'''<br />
{{Structure
|PDB= 1wma |SIZE=350|CAPTION= <scene name='initialview01'>1wma</scene>, resolution 1.24&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=AB3:3-(4-AMINO-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL)PHENOL'>AB3</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=PE5:3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL'>PE5</scene> and <scene name='pdbligand=P33:3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL'>P33</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Carbonyl_reductase_(NADPH) Carbonyl reductase (NADPH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.184 1.1.1.184]
|GENE=
}}
 
'''Crystal structure of human CBR1 in complex with Hydroxy-PP'''
 


==Overview==
==Overview==
Line 7: Line 16:


==About this Structure==
==About this Structure==
1WMA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=AB3:'>AB3</scene>, <scene name='pdbligand=NDP:'>NDP</scene>, <scene name='pdbligand=PE5:'>PE5</scene> and <scene name='pdbligand=P33:'>P33</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carbonyl_reductase_(NADPH) Carbonyl reductase (NADPH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.184 1.1.1.184] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WMA OCA].  
1WMA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WMA OCA].  


==Reference==
==Reference==
An unbiased cell morphology-based screen for new, biologically active small molecules., Tanaka M, Bateman R, Rauh D, Vaisberg E, Ramachandani S, Zhang C, Hansen KC, Burlingame AL, Trautman JK, Shokat KM, Adams CL, PLoS Biol. 2005 May;3(5):e128. Epub 2005 Apr 5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15799708 15799708]
An unbiased cell morphology-based screen for new, biologically active small molecules., Tanaka M, Bateman R, Rauh D, Vaisberg E, Ramachandani S, Zhang C, Hansen KC, Burlingame AL, Trautman JK, Shokat KM, Adams CL, PLoS Biol. 2005 May;3(5):e128. Epub 2005 Apr 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15799708 15799708]
[[Category: Carbonyl reductase (NADPH)]]
[[Category: Carbonyl reductase (NADPH)]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 24: Line 33:
[[Category: oxidoreductase]]
[[Category: oxidoreductase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:45:57 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:58:47 2008''
Retrieved from "https://proteopedia.org/1wma"