1wuq: Difference between revisions

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[[Image:1wuq.gif|left|200px]]<br /><applet load="1wuq" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1wuq.gif|left|200px]]
caption="1wuq, resolution 2.0&Aring;" />
 
'''Structure of GTP cyclohydrolase I Complexed with 8-oxo-GTP'''<br />
{{Structure
|PDB= 1wuq |SIZE=350|CAPTION= <scene name='initialview01'>1wuq</scene>, resolution 2.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=8GT:8-OXO-GUANOSINE-5'-TRIPHOSPHATE'>8GT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/GTP_cyclohydrolase_I GTP cyclohydrolase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.16 3.5.4.16]
|GENE=
}}
 
'''Structure of GTP cyclohydrolase I Complexed with 8-oxo-GTP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1WUQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=8GT:'>8GT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/GTP_cyclohydrolase_I GTP cyclohydrolase I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.16 3.5.4.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUQ OCA].  
1WUQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUQ OCA].  


==Reference==
==Reference==
Novel reaction mechanism of GTP cyclohydrolase I. High-resolution X-ray crystallography of Thermus thermophilus HB8 enzyme complexed with a transition state analogue, the 8-oxoguanine derivative., Tanaka Y, Nakagawa N, Kuramitsu S, Yokoyama S, Masui R, J Biochem. 2005 Sep;138(3):263-75. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16169877 16169877]
Novel reaction mechanism of GTP cyclohydrolase I. High-resolution X-ray crystallography of Thermus thermophilus HB8 enzyme complexed with a transition state analogue, the 8-oxoguanine derivative., Tanaka Y, Nakagawa N, Kuramitsu S, Yokoyama S, Masui R, J Biochem. 2005 Sep;138(3):263-75. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16169877 16169877]
[[Category: GTP cyclohydrolase I]]
[[Category: GTP cyclohydrolase I]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: beta barrel]]
[[Category: beta barrel]]
[[Category: hydrolase]]
[[Category: hydrolase]]
[[Category: national project on protein structural and functional analyses]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: nppsfa]]
[[Category: protein-inhibitor complex]]
[[Category: protein-inhibitor complex]]
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[[Category: riken structural genomics/proteomics initiative]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: rsgi]]
[[Category: structural genomics]]
[[Category: structural genomic]]
[[Category: tetrahydrobiopterin]]
[[Category: tetrahydrobiopterin]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:01:45 2008''
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