3zxa: Difference between revisions
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[[ | ==Structure and Assembly of Turnip Crinkle Virus I. X-ray Crystallographic Structure Analysis at 3.2 A Resolution== | ||
<StructureSection load='3zxa' size='340' side='right' caption='[[3zxa]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3zxa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Turnip_crinkle_virus Turnip crinkle virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZXA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZXA FirstGlance]. <br> | |||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zx8|3zx8]], [[3zx9|3zx9]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zxa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zxa RCSB], [http://www.ebi.ac.uk/pdbsum/3zxa PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CAPSD_TCV CAPSD_TCV]] Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins. Also acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.<ref>PMID:12477856</ref> <ref>PMID:12620795</ref> <ref>PMID:20439431</ref> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The structure of turnip crinkle virus has been determined at 3.2 A resolution, using the electron density of tomato bushy stunt virus as a starting point for phase refinement by non-crystallographic symmetry. The structures are very closely related, especially in the subunit arm and S domain, where only small insertions and deletions and small co-ordinate shifts relate one chain to another. The P domains, although quite similar in fold, are oriented somewhat differently with respect to the S domains. Understanding of the structure of turnip crinkle virus has been important for analyzing its assembly, as described in an accompanying paper. | |||
Structure and assembly of turnip crinkle virus. I. X-ray crystallographic structure analysis at 3.2 A resolution.,Hogle JM, Maeda A, Harrison SC J Mol Biol. 1986 Oct 20;191(4):625-38. PMID:3806676<ref>PMID:3806676</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
==See Also== | ==See Also== | ||
*[[Virus coat protein|Virus coat protein]] | *[[Virus coat protein|Virus coat protein]] | ||
== References == | |||
== | <references/> | ||
< | __TOC__ | ||
</StructureSection> | |||
[[Category: Turnip crinkle virus]] | [[Category: Turnip crinkle virus]] | ||
[[Category: Harrison, S C | [[Category: Harrison, S C]] | ||
[[Category: Hogle, J M | [[Category: Hogle, J M]] | ||
[[Category: Maeda, A | [[Category: Maeda, A]] | ||
[[Category: Icosahedral virus]] | [[Category: Icosahedral virus]] | ||
[[Category: Ssrna virus]] | [[Category: Ssrna virus]] | ||
[[Category: Virus]] | [[Category: Virus]] | ||
