4k6h: Difference between revisions
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<StructureSection load='4k6h' size='340' side='right' caption='[[4k6h]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='4k6h' size='340' side='right' caption='[[4k6h]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4k6h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Canar Canar]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6H OCA]. <br> | <table><tr><td colspan='2'>[[4k6h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Canar Canar]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K6H FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4k5q|4k5q]], [[4k6g|4k6g]], [[4k6k|4k6k]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4k5q|4k5q]], [[4k6g|4k6g]], [[4k6k|4k6k]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triacylglycerol_lipase Triacylglycerol lipase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.3 3.1.1.3] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k6h RCSB], [http://www.ebi.ac.uk/pdbsum/4k6h PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k6h RCSB], [http://www.ebi.ac.uk/pdbsum/4k6h PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/LIPB_CANAR LIPB_CANAR]] Hydrolysis of triglycerides. Is very stereospecific both in hydrolysis and in organic synthesis and has a potentially important application in glucolipid synthesis. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Enhanced enzyme kinetic stability by increasing rigidity within the active site.,Xie Y, An J, Yang G, Wu G, Zhang Y, Cui L, Feng Y J Biol Chem. 2014 Mar 14;289(11):7994-8006. doi: 10.1074/jbc.M113.536045. Epub, 2014 Jan 21. PMID:24448805<ref>PMID:24448805</ref> | Enhanced enzyme kinetic stability by increasing rigidity within the active site.,Xie Y, An J, Yang G, Wu G, Zhang Y, Cui L, Feng Y J Biol Chem. 2014 Mar 14;289(11):7994-8006. doi: 10.1074/jbc.M113.536045. Epub, 2014 Jan 21. PMID:24448805<ref>PMID:24448805</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
==See Also== | |||
*[[Lipase|Lipase]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Canar]] | [[Category: Canar]] | ||
[[Category: Triacylglycerol lipase]] | [[Category: Triacylglycerol lipase]] | ||
[[Category: An, J | [[Category: An, J]] | ||
[[Category: Feng, Y | [[Category: Feng, Y]] | ||
[[Category: Wu, G | [[Category: Wu, G]] | ||
[[Category: Xie, Y | [[Category: Xie, Y]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Lipase]] | [[Category: Lipase]] | ||