1x86: Difference between revisions

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[[Image:1x86.gif|left|200px]]<br /><applet load="1x86" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1x86.gif|left|200px]]
caption="1x86, resolution 3.22&Aring;" />
 
'''Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF in complex with RhoA'''<br />
{{Structure
|PDB= 1x86 |SIZE=350|CAPTION= <scene name='initialview01'>1x86</scene>, resolution 3.22&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE ION'>PO4</scene>
|ACTIVITY=
|GENE= ARHGEF12, LARG, KIAA0382 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), RHOA, ARHA, ARH12, RHO12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal Structure of the DH/PH domains of Leukemia-associated RhoGEF in complex with RhoA'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1X86 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=PO4:'>PO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X86 OCA].  
1X86 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X86 OCA].  


==Reference==
==Reference==
Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor., Kristelly R, Gao G, Tesmer JJ, J Biol Chem. 2004 Nov 5;279(45):47352-62. Epub 2004 Aug 25. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15331592 15331592]
Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor., Kristelly R, Gao G, Tesmer JJ, J Biol Chem. 2004 Nov 5;279(45):47352-62. Epub 2004 Aug 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15331592 15331592]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: helical bundle (dh)]]
[[Category: helical bundle (dh)]]


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