1xh2: Difference between revisions

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[[Image:1xh2.gif|left|200px]]<br /><applet load="1xh2" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1xh2.gif|left|200px]]
caption="1xh2, resolution 2.2&Aring;" />
 
'''Structure of the N298S variant of human pancreatic alpha-amylase complexed with chloride and acarbose'''<br />
{{Structure
|PDB= 1xh2 |SIZE=350|CAPTION= <scene name='initialview01'>1xh2</scene>, resolution 2.2&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ARE:ACARBOSE+DERIVED+PENTASACCHARIDE'>ARE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=CL:CHLORIDE ION'>CL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Alpha-amylase Alpha-amylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.1 3.2.1.1]
|GENE=
}}
 
'''Structure of the N298S variant of human pancreatic alpha-amylase complexed with chloride and acarbose'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1XH2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=ARE:'>ARE</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=CL:'>CL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Alpha-amylase Alpha-amylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.1 3.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XH2 OCA].  
1XH2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XH2 OCA].  


==Reference==
==Reference==
Structural and mechanistic studies of chloride induced activation of human pancreatic alpha-amylase., Maurus R, Begum A, Kuo HH, Racaza A, Numao S, Andersen C, Tams JW, Vind J, Overall CM, Withers SG, Brayer GD, Protein Sci. 2005 Mar;14(3):743-55. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15722449 15722449]
Structural and mechanistic studies of chloride induced activation of human pancreatic alpha-amylase., Maurus R, Begum A, Kuo HH, Racaza A, Numao S, Andersen C, Tams JW, Vind J, Overall CM, Withers SG, Brayer GD, Protein Sci. 2005 Mar;14(3):743-55. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15722449 15722449]
[[Category: Alpha-amylase]]
[[Category: Alpha-amylase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: inhibitor]]
[[Category: inhibitor]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:54:45 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:09:42 2008''
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