1xa6: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1xa6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XA6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1xa6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XA6 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xa6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xa6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xa6 RCSB], [http://www.ebi.ac.uk/pdbsum/1xa6 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xa6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xa6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xa6 RCSB], [http://www.ebi.ac.uk/pdbsum/1xa6 PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/CHIO_HUMAN CHIO_HUMAN]] GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and could therefore play a role in the progression from low-grade to high-grade tumors.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Canagarajah, B.]]
[[Category: Canagarajah, B]]
[[Category: Ho, J Y.]]
[[Category: Ho, J Y]]
[[Category: Hurley, J H.]]
[[Category: Hurley, J H]]
[[Category: Kazanietz, M G.]]
[[Category: Kazanietz, M G]]
[[Category: Leskow, F C.]]
[[Category: Leskow, F C]]
[[Category: Mischak, H.]]
[[Category: Mischak, H]]
[[Category: Saidi, L F.]]
[[Category: Saidi, L F]]
[[Category: Beta2-chimaerin]]
[[Category: Beta2-chimaerin]]
[[Category: C1]]
[[Category: C1]]
[[Category: Racgap]]
[[Category: Racgap]]
[[Category: Signaling protein]]
[[Category: Signaling protein]]