4e19: Difference between revisions

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[[~~Image~~:~~4e19~~.~~jpg~~|~~left~~|~~200px~~]]

==Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1==

== Structural highlights ==

<table><tr><td colspan='2'>[[4e19]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_sp._nrc-1 Halobacterium sp. nrc-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E19 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E19 FirstGlance].

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">VNG_0255C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=64091 Halobacterium sp. NRC-1])</td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e19 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4e19 RCSB], [http://www.ebi.ac.uk/pdbsum/4e19 PDBsum]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/RNH_HALSA RNH_HALSA]] Nuclease that specifically degrades the RNA of RNA-DNA hybrids; seems to act exonucleolytically on RNA/DNA hybrids. Endonucleolytically removes RNA primers from the Okazaki fragments of lagging strand synthesis on its own. Complements the temperature-sensitive phenotype of an E.coli double rnhA/rnhB (RNase H) disruption mutant.<ref>PMID:15115438</ref>

~~{{STRUCTURE_4e19| PDB=4e19 | SCENE= }}~~

==See Also==

*[[Ribonuclease|Ribonuclease]]

===~~Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1=~~==

*[[Temp|Temp]]

*[[User:Jaime.Prilusky/Test/tree|User:Jaime.Prilusky/Test/tree]]

== References ==

~~==About this Structure==~~

[[~~4e19~~]] ~~is a 2 chain structure with sequence from~~ [~~http~~://en.~~wikipedia.org~~/~~wiki~~/~~Halobacterium_sp._nrc-1 Halobacterium sp. nrc-1~~]~~. Full crystallographic information is available from [http:~~//~~oca.weizmann.ac.il/oca-bin/ocashort?id=4E19 OCA].~~

__TOC__

</StructureSection>

[[Category: Halobacterium sp. nrc-1]]

[[Category: Ribonuclease H]]

[[Category: Angkawidjaja, C.]]

[[Category: Angkawidjaja, C]]

[[Category: Kanaya, S.]]

[[Category: Kanaya, S]]

[[Category: Koga, Y.]]

[[Category: Koga, Y]]

[[Category: You, D J.]]

[[Category: You, D J]]

[[Category: Hydrolase]]

[[Category: Rnase h1]]

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@@ Line 1: / Line 1: @@
-[[Image:4e19.jpg|left|200px]]
+==Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1==
+<StructureSection load='4e19' size='340' side='right' caption='[[4e19]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4e19]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_sp._nrc-1 Halobacterium sp. nrc-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E19 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E19 FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VNG_0255C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=64091 Halobacterium sp. NRC-1])</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonuclease_H Ribonuclease H], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.4 3.1.26.4] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e19 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4e19 RCSB], [http://www.ebi.ac.uk/pdbsum/4e19 PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/RNH_HALSA RNH_HALSA]] Nuclease that specifically degrades the RNA of RNA-DNA hybrids; seems to act exonucleolytically on RNA/DNA hybrids. Endonucleolytically removes RNA primers from the Okazaki fragments of lagging strand synthesis on its own. Complements the temperature-sensitive phenotype of an E.coli double rnhA/rnhB (RNase H) disruption mutant.<ref>PMID:15115438</ref>
-{{STRUCTURE_4e19|  PDB=4e19  |  SCENE=  }}
+==See Also==
+*[[Ribonuclease|Ribonuclease]]
-===Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1===
+*[[Temp|Temp]]
+*[[User:Jaime.Prilusky/Test/tree|User:Jaime.Prilusky/Test/tree]]
+== References ==
-==About this Structure==
+<references/>
-[[4e19]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_sp._nrc-1 Halobacterium sp. nrc-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E19 OCA].
+__TOC__
+</StructureSection>
 [[Category: Halobacterium sp. nrc-1]]
 [[Category: Ribonuclease H]]
-[[Category: Angkawidjaja, C.]]
+[[Category: Angkawidjaja, C]]
-[[Category: Kanaya, S.]]
+[[Category: Kanaya, S]]
-[[Category: Koga, Y.]]
+[[Category: Koga, Y]]
-[[Category: You, D J.]]
+[[Category: You, D J]]
 [[Category: Hydrolase]]
 [[Category: Rnase h1]]