2vet: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2vet]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VET OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VET FirstGlance]. <br> | <table><tr><td colspan='2'>[[2vet]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VET OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VET FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jg0|1jg0]], [[1bid|1bid]], [[1jtu|1jtu]], [[1ddu|1ddu]], [[1bjg|1bjg]], [[1axw|1axw]], [[2ftq|2ftq]], [[1syn|1syn]], [[1tsd|1tsd]], [[1ffl|1ffl]], [[1bq1|1bq1]], [[2kce|2kce]], [[1evf|1evf]], [[2ftn|2ftn]], [[1dna|1dna]], [[1kce|1kce]], [[1jtq|1jtq]], [[1f4g|1f4g]], [[1f4f|1f4f]], [[1tjs|1tjs]], [[1fwm|1fwm]], [[1an5|1an5]], [[1f4c|1f4c]], [[1kzj|1kzj]], [[1trg|1trg]], [[2bbq|2bbq]], [[2g8o|2g8o]], [[1tys|1tys]], [[1nce|1nce]], [[1jut|1jut]], [[1tlc|1tlc]], [[2g8x|2g8x]], [[1evg|1evg]], [[1qqq|1qqq]], [[1ev8|1ev8]], [[1tls|1tls]], [[1f4b|1f4b]], [[1zpr|1zpr]], [[2fto|2fto]], [[1kzi|1kzi]], [[1f4e|1f4e]], [[1bdu|1bdu]], [[3tms|3tms]], [[2a9w|2a9w]], [[1tdu|1tdu]], [[2g8m|2g8m]], [[1aob|1aob]], [[1bq2|1bq2]], [[1aiq|1aiq]], [[1f4d|1f4d]], [[1ev5|1ev5]], [[1ajm|1ajm]], [[2tsc|2tsc]], [[1tsn|1tsn]], [[2vf0|2vf0]], [[3b5b|3b5b]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jg0|1jg0]], [[1bid|1bid]], [[1jtu|1jtu]], [[1ddu|1ddu]], [[1bjg|1bjg]], [[1axw|1axw]], [[2ftq|2ftq]], [[1syn|1syn]], [[1tsd|1tsd]], [[1ffl|1ffl]], [[1bq1|1bq1]], [[2kce|2kce]], [[1evf|1evf]], [[2ftn|2ftn]], [[1dna|1dna]], [[1kce|1kce]], [[1jtq|1jtq]], [[1f4g|1f4g]], [[1f4f|1f4f]], [[1tjs|1tjs]], [[1fwm|1fwm]], [[1an5|1an5]], [[1f4c|1f4c]], [[1kzj|1kzj]], [[1trg|1trg]], [[2bbq|2bbq]], [[2g8o|2g8o]], [[1tys|1tys]], [[1nce|1nce]], [[1jut|1jut]], [[1tlc|1tlc]], [[2g8x|2g8x]], [[1evg|1evg]], [[1qqq|1qqq]], [[1ev8|1ev8]], [[1tls|1tls]], [[1f4b|1f4b]], [[1zpr|1zpr]], [[2fto|2fto]], [[1kzi|1kzi]], [[1f4e|1f4e]], [[1bdu|1bdu]], [[3tms|3tms]], [[2a9w|2a9w]], [[1tdu|1tdu]], [[2g8m|2g8m]], [[1aob|1aob]], [[1bq2|1bq2]], [[1aiq|1aiq]], [[1f4d|1f4d]], [[1ev5|1ev5]], [[1ajm|1ajm]], [[2tsc|2tsc]], [[1tsn|1tsn]], [[2vf0|2vf0]], [[3b5b|3b5b]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vet FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vet OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vet RCSB], [http://www.ebi.ac.uk/pdbsum/2vet PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vet FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vet OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2vet RCSB], [http://www.ebi.ac.uk/pdbsum/2vet PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/TYSY_ECOLI TYSY_ECOLI]] Provides the sole de novo source of dTMP for DNA biosynthesis. This protein also binds to its mRNA thus repressing its own translation. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 35: | Line 37: | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Thymidylate synthase]] | [[Category: Thymidylate synthase]] | ||
[[Category: Arreola, R | [[Category: Arreola, R]] | ||
[[Category: Maley, F | [[Category: Maley, F]] | ||
[[Category: Montfort, W R | [[Category: Montfort, W R]] | ||
[[Category: Sotelo-Mundo, R R | [[Category: Sotelo-Mundo, R R]] | ||
[[Category: Dump substrate]] | [[Category: Dump substrate]] | ||
[[Category: Methyltransferase]] | [[Category: Methyltransferase]] | ||
| Line 44: | Line 46: | ||
[[Category: Repressor]] | [[Category: Repressor]] | ||
[[Category: Rna-binding]] | [[Category: Rna-binding]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Translation regulation]] | [[Category: Translation regulation]] | ||
