2thi: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2thi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Paenibacillus_thiaminolyticus Paenibacillus thiaminolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2THI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2THI FirstGlance]. <br> | <table><tr><td colspan='2'>[[2thi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Paenibacillus_thiaminolyticus Paenibacillus thiaminolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2THI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2THI FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thiamine_pyridinylase Thiamine pyridinylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.2 2.5.1.2] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thiamine_pyridinylase Thiamine pyridinylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.2 2.5.1.2] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2thi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2thi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2thi RCSB], [http://www.ebi.ac.uk/pdbsum/2thi PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2thi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2thi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2thi RCSB], [http://www.ebi.ac.uk/pdbsum/2thi PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/THI1_PANTH THI1_PANTH]] Degrades thiamine by replacing its thiazole moiety with a wide range of nucleophiles. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Paenibacillus thiaminolyticus]] | [[Category: Paenibacillus thiaminolyticus]] | ||
[[Category: Thiamine pyridinylase]] | [[Category: Thiamine pyridinylase]] | ||
[[Category: Begley, T P | [[Category: Begley, T P]] | ||
[[Category: Campobasso, N | [[Category: Campobasso, N]] | ||
[[Category: Ealick, S E | [[Category: Ealick, S E]] | ||
[[Category: Thiamine degradation]] | [[Category: Thiamine degradation]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
