1yc5: Difference between revisions

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[[Image:1yc5.gif|left|200px]]<br /><applet load="1yc5" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1yc5.gif|left|200px]]
caption="1yc5, resolution 1.40&Aring;" />
 
'''Sir2-p53 peptide-nicotinamide'''<br />
{{Structure
|PDB= 1yc5 |SIZE=350|CAPTION= <scene name='initialview01'>1yc5</scene>, resolution 1.40&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=NCA:NICOTINAMIDE'>NCA</scene>
|ACTIVITY=
|GENE= npdA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])
}}
 
'''Sir2-p53 peptide-nicotinamide'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1YC5 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=NCA:'>NCA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YC5 OCA].  
1YC5 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YC5 OCA].  


==Reference==
==Reference==
Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme., Avalos JL, Bever KM, Wolberger C, Mol Cell. 2005 Mar 18;17(6):855-68. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15780941 15780941]
Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme., Avalos JL, Bever KM, Wolberger C, Mol Cell. 2005 Mar 18;17(6):855-68. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15780941 15780941]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: sirtuin]]
[[Category: sirtuin]]


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