1yim: Difference between revisions
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[[Image:1yim.gif|left|200px]] | [[Image:1yim.gif|left|200px]] | ||
'''Human estrogen receptor alpha ligand-binding domain in complex with compound 4''' | {{Structure | ||
|PDB= 1yim |SIZE=350|CAPTION= <scene name='initialview01'>1yim</scene>, resolution 1.90Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=CM4:(2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL'>CM4</scene> | |||
|ACTIVITY= | |||
|GENE= ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Human estrogen receptor alpha ligand-binding domain in complex with compound 4''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1YIM is a [ | 1YIM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YIM OCA]. | ||
==Reference== | ==Reference== | ||
Estrogen receptor ligands. Part 10: Chromanes: old scaffolds for new SERAMs., Tan Q, Blizzard TA, Morgan JD 2nd, Birzin ET, Chan W, Yang YT, Pai LY, Hayes EC, DaSilva CA, Warrier S, Yudkovitz J, Wilkinson HA, Sharma N, Fitzgerald PM, Li S, Colwell L, Fisher JE, Adamski S, Reszka AA, Kimmel D, DiNinno F, Rohrer SP, Freedman LP, Schaeffer JM, Hammond ML, Bioorg Med Chem Lett. 2005 Mar 15;15(6):1675-81. PMID:[http:// | Estrogen receptor ligands. Part 10: Chromanes: old scaffolds for new SERAMs., Tan Q, Blizzard TA, Morgan JD 2nd, Birzin ET, Chan W, Yang YT, Pai LY, Hayes EC, DaSilva CA, Warrier S, Yudkovitz J, Wilkinson HA, Sharma N, Fitzgerald PM, Li S, Colwell L, Fisher JE, Adamski S, Reszka AA, Kimmel D, DiNinno F, Rohrer SP, Freedman LP, Schaeffer JM, Hammond ML, Bioorg Med Chem Lett. 2005 Mar 15;15(6):1675-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15745820 15745820] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: transcription factor]] | [[Category: transcription factor]] | ||
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