1ypl: Difference between revisions

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[[Image:1ypl.gif|left|200px]]<br /><applet load="1ypl" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ypl.gif|left|200px]]
caption="1ypl, resolution 1.85&Aring;" />
 
'''X-ray crystal structure of thrombin inhibited by synthetic cyanopeptide analogue RA-1008'''<br />
{{Structure
|PDB= 1ypl |SIZE=350|CAPTION= <scene name='initialview01'>1ypl</scene>, resolution 1.85&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RA8:N-(BENZYLSULFONYL)-L-LEUCYL-N-(4-{[AMINO(IMINO)METHYL]AMINO}BUTYL)-L-PROLINAMIDE'>RA8</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
|GENE=
}}
 
'''X-ray crystal structure of thrombin inhibited by synthetic cyanopeptide analogue RA-1008'''
 


==Disease==
==Disease==
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==About this Structure==
==About this Structure==
1YPL is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=RA8:'>RA8</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPL OCA].  
1YPL is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPL OCA].  
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: thrombin]]
[[Category: thrombin]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:07:44 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:25:52 2008''

Revision as of 13:25, 20 March 2008

File:1ypl.gif


Drag the structure with the mouse to rotate
1ypl, resolution 1.85Å
Ligands: NA, RA8 and GOL
Activity: Thrombin, with EC number 3.4.21.5
Coordinates: save as pdb, mmCIF, xml



X-ray crystal structure of thrombin inhibited by synthetic cyanopeptide analogue RA-1008


Disease

Known diseases associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this Structure

1YPL is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 15:25:52 2008

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