1yvf: Difference between revisions

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[[Image:1yvf.gif|left|200px]]<br /><applet load="1yvf" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1yvf.gif|left|200px]]
caption="1yvf, resolution 2.500&Aring;" />
 
'''Hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00729145'''<br />
{{Structure
|PDB= 1yvf |SIZE=350|CAPTION= <scene name='initialview01'>1yvf</scene>, resolution 2.500&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PH7:(2Z)-2-(BENZOYLAMINO)-3-[4-(2-BROMOPHENOXY)PHENYL]-2-PROPENOIC+ACID'>PH7</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48]
|GENE=
}}
 
'''Hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00729145'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1YVF is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus] with <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=PH7:'>PH7</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YVF OCA].  
1YVF is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YVF OCA].  


==Reference==
==Reference==
Inhibitors of HCV NS5B polymerase. Part 1: Evaluation of the southern region of (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid., Pfefferkorn JA, Greene ML, Nugent RA, Gross RJ, Mitchell MA, Finzel BC, Harris MS, Wells PA, Shelly JA, Anstadt RA, Kilkuskie RE, Kopta LA, Schwende FJ, Bioorg Med Chem Lett. 2005 May 16;15(10):2481-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15863301 15863301]
Inhibitors of HCV NS5B polymerase. Part 1: Evaluation of the southern region of (2Z)-2-(benzoylamino)-3-(5-phenyl-2-furyl)acrylic acid., Pfefferkorn JA, Greene ML, Nugent RA, Gross RJ, Mitchell MA, Finzel BC, Harris MS, Wells PA, Shelly JA, Anstadt RA, Kilkuskie RE, Kopta LA, Schwende FJ, Bioorg Med Chem Lett. 2005 May 16;15(10):2481-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15863301 15863301]
[[Category: Hepatitis c virus]]
[[Category: Hepatitis c virus]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: PH7]]
[[Category: PH7]]
[[Category: PO4]]
[[Category: PO4]]
[[Category: fingers]]
[[Category: finger]]
[[Category: hcv]]
[[Category: hcv]]
[[Category: ns5b]]
[[Category: ns5b]]
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[[Category: thumb]]
[[Category: thumb]]


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Retrieved from "https://proteopedia.org/1yvf"