1yvj: Difference between revisions

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[[Image:1yvj.gif|left|200px]]<br /><applet load="1yvj" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1yvj.gif|left|200px]]
caption="1yvj, resolution 2.55&Aring;" />
 
'''Crystal structure of the Jak3 kinase domain in complex with a staurosporine analogue'''<br />
{{Structure
|PDB= 1yvj |SIZE=350|CAPTION= <scene name='initialview01'>1yvj</scene>, resolution 2.55&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=DTV:(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL'>DTV</scene> and <scene name='pdbligand=4ST:1,2,3,4-TETRAHYDROGEN-STAUROSPORINE'>4ST</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2]
|GENE= JAK3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of the Jak3 kinase domain in complex with a staurosporine analogue'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1YVJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=DTV:'>DTV</scene> and <scene name='pdbligand=4ST:'>4ST</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YVJ OCA].  
1YVJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YVJ OCA].  


==Reference==
==Reference==
Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog., Boggon TJ, Li Y, Manley PW, Eck MJ, Blood. 2005 Aug 1;106(3):996-1002. Epub 2005 Apr 14. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15831699 15831699]
Crystal structure of the Jak3 kinase domain in complex with a staurosporine analog., Boggon TJ, Li Y, Manley PW, Eck MJ, Blood. 2005 Aug 1;106(3):996-1002. Epub 2005 Apr 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15831699 15831699]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: tyrosine kinase; scid; severe combined immunodeficiency; stat5; stat6; interleukin-2; common-gamma chain]]
[[Category: tyrosine kinase; scid; severe combined immunodeficiency; stat5; stat6; interleukin-2; common-gamma chain]]


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