1yvx: Difference between revisions

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[[Image:1yvx.gif|left|200px]]<br /><applet load="1yvx" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1yvx.gif|left|200px]]
caption="1yvx, resolution 2.00&Aring;" />
 
'''Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor'''<br />
{{Structure
|PDB= 1yvx |SIZE=350|CAPTION= <scene name='initialview01'>1yvx</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=IPC:3-[ISOPROPYL(4-METHYLBENZOYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID'>IPC</scene>
|ACTIVITY=
|GENE=
}}
 
'''Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1YVX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=IPC:'>IPC</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YVX OCA].  
1YVX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YVX OCA].  


==Reference==
==Reference==
Crystal structures of the RNA-dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors., Biswal BK, Cherney MM, Wang M, Chan L, Yannopoulos CG, Bilimoria D, Nicolas O, Bedard J, James MN, J Biol Chem. 2005 May 6;280(18):18202-10. Epub 2005 Mar 2. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15746101 15746101]
Crystal structures of the RNA-dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors., Biswal BK, Cherney MM, Wang M, Chan L, Yannopoulos CG, Bilimoria D, Nicolas O, Bedard J, James MN, J Biol Chem. 2005 May 6;280(18):18202-10. Epub 2005 Mar 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15746101 15746101]
[[Category: Hepatitis c virus]]
[[Category: Hepatitis c virus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: ns5b polymerase genotype 2a]]
[[Category: ns5b polymerase genotype 2a]]


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