4pe0: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pe0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pe0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pe0 RCSB], [http://www.ebi.ac.uk/pdbsum/4pe0 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pe0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pe0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pe0 RCSB], [http://www.ebi.ac.uk/pdbsum/4pe0 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/S100B_BOVIN S100B_BOVIN]] Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization (By similarity).<ref>PMID:14661952</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Cavalier, M C | [[Category: Cavalier, M C]] | ||
[[Category: Neau, D | [[Category: Neau, D]] | ||
[[Category: Pierce, P D | [[Category: Pierce, P D]] | ||
[[Category: Toth, E A | [[Category: Toth, E A]] | ||
[[Category: Weber, D J | [[Category: Weber, D J]] | ||
[[Category: Wilder, P T | [[Category: Wilder, P T]] | ||
[[Category: Calcium binding]] | [[Category: Calcium binding]] | ||
[[Category: Complex]] | [[Category: Complex]] | ||
