1zd2: Difference between revisions

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[[Image:1zd2.gif|left|200px]]<br /><applet load="1zd2" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1zd2.gif|left|200px]]
caption="1zd2, resolution 3.&Aring;" />
 
'''Human soluble epoxide hydrolase 4-(3-cyclohexyluriedo)-ethanoic acid complex'''<br />
{{Structure
|PDB= 1zd2 |SIZE=350|CAPTION= <scene name='initialview01'>1zd2</scene>, resolution 3.&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> and <scene name='pdbligand=NC3:N-[(CYCLOHEXYLAMINO)CARBONYL]GLYCINE'>NC3</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Microsomal_epoxide_hydrolase Microsomal epoxide hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.3.2.9 3.3.2.9]
|GENE= EPHX2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Human soluble epoxide hydrolase 4-(3-cyclohexyluriedo)-ethanoic acid complex'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1ZD2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=PO4:'>PO4</scene> and <scene name='pdbligand=NC3:'>NC3</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Microsomal_epoxide_hydrolase Microsomal epoxide hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.3.2.9 3.3.2.9] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZD2 OCA].  
1ZD2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZD2 OCA].  


==Reference==
==Reference==
Human soluble epoxide hydrolase: structural basis of inhibition by 4-(3-cyclohexylureido)-carboxylic acids., Gomez GA, Morisseau C, Hammock BD, Christianson DW, Protein Sci. 2006 Jan;15(1):58-64. Epub 2005 Dec 1. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16322563 16322563]
Human soluble epoxide hydrolase: structural basis of inhibition by 4-(3-cyclohexylureido)-carboxylic acids., Gomez GA, Morisseau C, Hammock BD, Christianson DW, Protein Sci. 2006 Jan;15(1):58-64. Epub 2005 Dec 1. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16322563 16322563]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Microsomal epoxide hydrolase]]
[[Category: Microsomal epoxide hydrolase]]
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[[Category: domain-swapped dimer]]
[[Category: domain-swapped dimer]]


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