1zm7: Difference between revisions

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[[Image:1zm7.gif|left|200px]]<br /><applet load="1zm7" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1zm7.gif|left|200px]]
caption="1zm7, resolution 2.20&Aring;" />
 
'''Crystal structure of D. melanogaster deoxyribonucleoside kinase mutant N64D in complex with dTTP'''<br />
{{Structure
|PDB= 1zm7 |SIZE=350|CAPTION= <scene name='initialview01'>1zm7</scene>, resolution 2.20&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=TTP:THYMIDINE-5'-TRIPHOSPHATE'>TTP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145]
|GENE= dnk ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])
}}
 
'''Crystal structure of D. melanogaster deoxyribonucleoside kinase mutant N64D in complex with dTTP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1ZM7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=TTP:'>TTP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Deoxynucleoside_kinase Deoxynucleoside kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.145 2.7.1.145] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZM7 OCA].  
1ZM7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZM7 OCA].  


==Reference==
==Reference==
Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D., Welin M, Skovgaard T, Knecht W, Zhu C, Berenstein D, Munch-Petersen B, Piskur J, Eklund H, FEBS J. 2005 Jul;272(14):3733-42. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16008571 16008571]
Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D., Welin M, Skovgaard T, Knecht W, Zhu C, Berenstein D, Munch-Petersen B, Piskur J, Eklund H, FEBS J. 2005 Jul;272(14):3733-42. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16008571 16008571]
[[Category: Deoxynucleoside kinase]]
[[Category: Deoxynucleoside kinase]]
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: n64d]]
[[Category: n64d]]


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