1zoh: Difference between revisions

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[[Image:1zoh.gif|left|200px]]<br /><applet load="1zoh" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1zoh.gif|left|200px]]
caption="1zoh, resolution 1.81&Aring;" />
 
'''Crystal structure of protein kinase CK2 in complex with TBB-derivatives inhibitors'''<br />
{{Structure
|PDB= 1zoh |SIZE=350|CAPTION= <scene name='initialview01'>1zoh</scene>, resolution 1.81&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K44:5,6,7,8-TETRABROMO-1-METHYL-2,3-DIHYDRO-1H-IMIDAZO[1,2-A]BENZIMIDAZOLE'>K44</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
|GENE= ACK2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4577 Zea mays])
}}
 
'''Crystal structure of protein kinase CK2 in complex with TBB-derivatives inhibitors'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1ZOH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays] with <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=K44:'>K44</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZOH OCA].  
1ZOH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZOH OCA].  


==Reference==
==Reference==
Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole., Battistutta R, Mazzorana M, Sarno S, Kazimierczuk Z, Zanotti G, Pinna LA, Chem Biol. 2005 Nov;12(11):1211-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16298300 16298300]
Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole., Battistutta R, Mazzorana M, Sarno S, Kazimierczuk Z, Zanotti G, Pinna LA, Chem Biol. 2005 Nov;12(11):1211-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16298300 16298300]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: K44]]
[[Category: K44]]
[[Category: NA]]
[[Category: NA]]
[[Category: inhibitors]]
[[Category: inhibitor]]
[[Category: pharmacophore]]
[[Category: pharmacophore]]
[[Category: protein kinase ck2]]
[[Category: protein kinase ck2]]
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[[Category: tetrabromo-benzimidazole]]
[[Category: tetrabromo-benzimidazole]]


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