1k0k: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1k0k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K0K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K0K FirstGlance]. <br> | <table><tr><td colspan='2'>[[1k0k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K0K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K0K FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ypr|1ypr]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ypr|1ypr]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k0k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1k0k RCSB], [http://www.ebi.ac.uk/pdbsum/1k0k PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k0k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1k0k RCSB], [http://www.ebi.ac.uk/pdbsum/1k0k PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/PROF_YEAST PROF_YEAST]] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Almo, S C | [[Category: Almo, S C]] | ||
[[Category: Fedorov, A A | [[Category: Fedorov, A A]] | ||
[[Category: Vorobiev, S | [[Category: Vorobiev, S]] | ||
[[Category: Actin-binding protein]] | [[Category: Actin-binding protein]] | ||
[[Category: Contractile protein]] | [[Category: Contractile protein]] | ||
[[Category: Pip2 binding protein]] | [[Category: Pip2 binding protein]] | ||
[[Category: Poly-l-proline binding protein]] | [[Category: Poly-l-proline binding protein]] | ||
Revision as of 21:51, 24 December 2014
Yeast Profilin, Cubic Crystal Form
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