4bit: Difference between revisions
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==solution structure of cerebral dopamine neurotrophic factor (CDNF)== | |||
<StructureSection load='4bit' size='340' side='right' caption='[[4bit]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |||
== Structural highlights == | |||
==Function== | <table><tr><td colspan='2'>[[4bit]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BIT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BIT FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bit OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bit RCSB], [http://www.ebi.ac.uk/pdbsum/4bit PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CDNF_HUMAN CDNF_HUMAN]] Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity). | [[http://www.uniprot.org/uniprot/CDNF_HUMAN CDNF_HUMAN]] Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity). | ||
__TOC__ | |||
</StructureSection> | |||
[[ | [[Category: Human]] | ||
[[Category: Almeida, m s | [[Category: Almeida, m s]] | ||
[[Category: Cabral, k m.s | [[Category: Cabral, k m.s]] | ||
[[Category: Foguel, d | [[Category: Foguel, d]] | ||
[[Category: Herrmann, t | [[Category: Herrmann, t]] | ||
[[Category: Latge, c | [[Category: Latge, c]] | ||
[[Category: Raymundo, d p | [[Category: Raymundo, d p]] | ||
[[Category: Parkinson]] | [[Category: Parkinson]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
