4gpu: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gpu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gpu RCSB], [http://www.ebi.ac.uk/pdbsum/4gpu PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gpu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gpu RCSB], [http://www.ebi.ac.uk/pdbsum/4gpu PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/Q6CPU0_KLULA Q6CPU0_KLULA]] Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping and 5'-3' exonuclease activities. Has decapping activity toward incomplete 5' end cap mRNAs such as unmethylated 5' end-capped RNA to release GpppN and 5' end monophosphate RNA. The 5' end monophosphate RNA is then degraded by the 5'-3' exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs.<ref>PMID:22961381</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
