4j07: Difference between revisions

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~~[[Image:4j07.jpg|left|200px]]~~

==Crystal structure of a PROBABLE RIBOFLAVIN SYNTHASE, BETA CHAIN RIBH (6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, Lumazine synthase) from Mycobacterium leprae==

~~{{STRUCTURE_4j07| PDB=4j07 | SCENE= }}~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4j07]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_leprae_br4923 Mycobacterium leprae br4923]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J07 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J07 FirstGlance].

===Crystal structure of a PROBABLE RIBOFLAVIN SYNTHASE, BETA CHAIN RIBH (6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, Lumazine synthase) from Mycobacterium leprae===

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">MLBr00560, ribH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=561304 Mycobacterium leprae Br4923])</td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/6,7-dimethyl-8-ribityllumazine_synthase 6,7-dimethyl-8-ribityllumazine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.78 2.5.1.78] </td></tr>

==~~About this Structure~~==

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j07 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j07 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4j07 RCSB], [http://www.ebi.ac.uk/pdbsum/4j07 PDBsum]</td></tr>

[[4j07]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_leprae_br4923 Mycobacterium leprae br4923]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J07 OCA].

</table>

== Function ==

[[http://www.uniprot.org/uniprot/RISB_MYCLB RISB_MYCLB]] Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.[HAMAP-Rule:MF_00178]

__TOC__

</StructureSection>

[[Category: 6,7-dimethyl-8-ribityllumazine synthase]]

[[Category: Mycobacterium leprae br4923]]

[[Category: ~~SSGCID, Seattle~~ Structural ~~Genomics Center for Infectious Disease.~~]]

[[Category: Structural genomic]]

[[Category: 7-dimethyl-8-ribityllumazine synthase]]

[[Category: Dmrl synthase]]

[[Category: Lumazine synthase]]

[[Category: Mycobacterium leprae]]

~~[[Category: Seattle structural genomics center for infectious disease]]~~

[[Category: Ssgcid]]

~~[[Category: Structural genomic]]~~

[[Category: Transferase]]

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-[[Image:4j07.jpg|left|200px]]
+==Crystal structure of a PROBABLE RIBOFLAVIN SYNTHASE, BETA CHAIN RIBH (6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, Lumazine synthase) from Mycobacterium leprae==
+<StructureSection load='4j07' size='340' side='right' caption='[[4j07]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
-{{STRUCTURE_4j07|  PDB=4j07  |  SCENE=  }}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4j07]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_leprae_br4923 Mycobacterium leprae br4923]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J07 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J07 FirstGlance]. <br>
-===Crystal structure of a PROBABLE RIBOFLAVIN SYNTHASE, BETA CHAIN RIBH (6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, Lumazine synthase) from Mycobacterium leprae===
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MLBr00560, ribH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=561304 Mycobacterium leprae Br4923])</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/6,7-dimethyl-8-ribityllumazine_synthase 6,7-dimethyl-8-ribityllumazine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.78 2.5.1.78] </span></td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j07 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j07 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4j07 RCSB], [http://www.ebi.ac.uk/pdbsum/4j07 PDBsum]</span></td></tr>
-[[4j07]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_leprae_br4923 Mycobacterium leprae br4923]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J07 OCA].
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/RISB_MYCLB RISB_MYCLB]] Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.[HAMAP-Rule:MF_00178]
+__TOC__
+</StructureSection>
 [[Category: 6,7-dimethyl-8-ribityllumazine synthase]]
 [[Category: Mycobacterium leprae br4923]]
-[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
+[[Category: Structural genomic]]
 [[Category: 7-dimethyl-8-ribityllumazine synthase]]
 [[Category: Dmrl synthase]]
 [[Category: Lumazine synthase]]
 [[Category: Mycobacterium leprae]]
-[[Category: Seattle structural genomics center for infectious disease]]
 [[Category: Ssgcid]]
-[[Category: Structural genomic]]
 [[Category: Transferase]]