2a5k: Difference between revisions

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[[Image:2a5k.gif|left|200px]]<br /><applet load="2a5k" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2a5k.gif|left|200px]]
caption="2a5k, resolution 2.30&Aring;" />
 
'''Crystal structures of SARS coronavirus main peptidase inhibited by an aza-peptide epoxide in space group P212121'''<br />
{{Structure
|PDB= 2a5k |SIZE=350|CAPTION= <scene name='initialview01'>2a5k</scene>, resolution 2.30&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=AZP:(5S,8S,14R)-ETHYL 11-(3-AMINO-3-OXOPROPYL)-8-BENZYL-14-HYDROXY-5-ISOBUTYL-3,6,9,12-TETRAOXO-1-PHENYL-2-OXA-4,7,10,11-TETRAAZAPENTADECAN-15-OATE'>AZP</scene>
|ACTIVITY=
|GENE=
}}
 
'''Crystal structures of SARS coronavirus main peptidase inhibited by an aza-peptide epoxide in space group P212121'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2A5K is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_sars_coronavirus Human sars coronavirus] with <scene name='pdbligand=AZP:'>AZP</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A5K OCA].  
2A5K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_sars_coronavirus Human sars coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A5K OCA].  


==Reference==
==Reference==
Crystal structures of the main peptidase from the SARS coronavirus inhibited by a substrate-like aza-peptide epoxide., Lee TW, Cherney MM, Huitema C, Liu J, James KE, Powers JC, Eltis LD, James MN, J Mol Biol. 2005 Nov 11;353(5):1137-51. Epub 2005 Sep 27. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16219322 16219322]
Crystal structures of the main peptidase from the SARS coronavirus inhibited by a substrate-like aza-peptide epoxide., Lee TW, Cherney MM, Huitema C, Liu J, James KE, Powers JC, Eltis LD, James MN, J Mol Biol. 2005 Nov 11;353(5):1137-51. Epub 2005 Sep 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16219322 16219322]
[[Category: Human sars coronavirus]]
[[Category: Human sars coronavirus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: long loop]]
[[Category: long loop]]
[[Category: n-finger]]
[[Category: n-finger]]
[[Category: specificity pockets]]
[[Category: specificity pocket]]
[[Category: substrate-like inhibitor]]
[[Category: substrate-like inhibitor]]


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