4mpg: Difference between revisions
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==Crystal structure of human glutathione transferase theta-2, complex with glutathione and unknown ligand, target EFI-507257== | |||
<StructureSection load='4mpg' size='340' side='right' caption='[[4mpg]], [[Resolution|resolution]] 1.95Å' scene=''> | |||
== Structural highlights == | |||
==Function== | <table><tr><td colspan='2'>[[4mpg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MPG FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr> | |||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mpf|4mpf]]</td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GSTT2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mpg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mpg RCSB], [http://www.ebi.ac.uk/pdbsum/4mpg PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/GST2_HUMAN GST2_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity. | [[http://www.uniprot.org/uniprot/GST2_HUMAN GST2_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity. | ||
== | ==See Also== | ||
[[ | *[[Glutathione S-transferase|Glutathione S-transferase]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Glutathione transferase]] | [[Category: Glutathione transferase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Almo, S C | [[Category: Almo, S C]] | ||
[[Category: Armstrong, R N | [[Category: Armstrong, R N]] | ||
[[Category: Bhosle, R | [[Category: Bhosle, R]] | ||
[[Category: Chowdhury, S | [[Category: Chowdhury, S]] | ||
[[Category: EFI, Enzyme Function Initiative | [[Category: EFI, Enzyme Function Initiative]] | ||
[[Category: Evans, B | [[Category: Evans, B]] | ||
[[Category: Gerlt, J A | [[Category: Gerlt, J A]] | ||
[[Category: Glenn, A Scott | [[Category: Glenn, A Scott]] | ||
[[Category: Hammonds, J | [[Category: Hammonds, J]] | ||
[[Category: Hillerich, B | [[Category: Hillerich, B]] | ||
[[Category: Imker, H J | [[Category: Imker, H J]] | ||
[[Category: Love, J | [[Category: Love, J]] | ||
[[Category: Obaidi, N Al | [[Category: Obaidi, N Al]] | ||
[[Category: Patskovsky, Y | [[Category: Patskovsky, Y]] | ||
[[Category: Seidel, R D | [[Category: Seidel, R D]] | ||
[[Category: Stead, M | [[Category: Stead, M]] | ||
[[Category: Toro, R | [[Category: Toro, R]] | ||
[[Category: Washington, E | [[Category: Washington, E]] | ||
[[Category: Efi]] | [[Category: Efi]] | ||
[[Category: Enzyme function initiative]] | [[Category: Enzyme function initiative]] | ||
