2acq: Difference between revisions

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[[Image:2acq.jpg|left|200px]]~~<br /><applet load~~="2acq~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:2acq.jpg|left|200px]]

~~caption="~~2acq, resolution 1.76Å" />

'''AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6-PHOSPHATE'''~~<br />~~

{{Structure

|PDB= 2acq |SIZE=350|CAPTION= <scene name='initialview01'>2acq</scene>, resolution 1.76Å

|SITE=

|LIGAND= <scene name='pdbligand=G6P:ALPHA-D-GLUCOSE-6-PHOSPHATE'>G6P</scene> and <scene name='pdbligand=NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE'>NAP</scene>

|ACTIVITY= [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21]

|GENE=

}}

'''AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6-PHOSPHATE'''

==Overview==

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==About this Structure==

2ACQ is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens~~] with <scene name='pdbligand=G6P:'>G6P</scene> and <scene name='pdbligand=NAP:'>NAP</scene> as [http://en.wikipedia.org/wiki/ligands ligands~~]. ~~Active as [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21]~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ACQ OCA].

2ACQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ACQ OCA].

==Reference==

An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate., Harrison DH, Bohren KM, Ringe D, Petsko GA, Gabbay KH, Biochemistry. 1994 Mar 1;33(8):2011-20. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~8117658 8117658]

An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate., Harrison DH, Bohren KM, Ringe D, Petsko GA, Gabbay KH, Biochemistry. 1994 Mar 1;33(8):2011-20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8117658 8117658]

[[Category: Aldehyde reductase]]

[[Category: Homo sapiens]]

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[[Category: oxidoreductase]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:48:04 2008''

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@@ Line 1: / Line 1: @@
-[[Image:2acq.jpg|left|200px]]<br /><applet load="2acq" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2acq.jpg|left|200px]]
-caption="2acq, resolution 1.76&Aring;" />
-'''AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6-PHOSPHATE'''<br />
+ {{Structure
+|PDB= 2acq |SIZE=350|CAPTION= <scene name='initialview01'>2acq</scene>, resolution 1.76&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=G6P:ALPHA-D-GLUCOSE-6-PHOSPHATE'>G6P</scene> and <scene name='pdbligand=NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE'>NAP</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21]
+|GENE=
+}}
+'''AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6-PHOSPHATE'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-ACQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=G6P:'>G6P</scene> and <scene name='pdbligand=NAP:'>NAP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ACQ OCA].
+ACQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ACQ OCA].
 ==Reference==
-An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate., Harrison DH, Bohren KM, Ringe D, Petsko GA, Gabbay KH, Biochemistry. 1994 Mar 1;33(8):2011-20. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8117658 8117658]
+An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate., Harrison DH, Bohren KM, Ringe D, Petsko GA, Gabbay KH, Biochemistry. 1994 Mar 1;33(8):2011-20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8117658 8117658]
 [[Category: Aldehyde reductase]]
 [[Category: Homo sapiens]]
@@ Line 23: / Line 32: @@
 [[Category: oxidoreductase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:26:06 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:48:04 2008''