2ada: Difference between revisions

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[[Image:2ada.gif|left|200px]]<br /><applet load="2ada" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ada.gif|left|200px]]
caption="2ada, resolution 2.4&Aring;" />
 
'''ATOMIC STRUCTURE OF ADENOSINE DEAMINASE COMPLEXED WITH A TRANSITION-STATE ANALOG: UNDERSTANDING CATALYSIS AND IMMUNODEFICIENCY MUTATIONS'''<br />
{{Structure
|PDB= 2ada |SIZE=350|CAPTION= <scene name='initialview01'>2ada</scene>, resolution 2.4&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=HPR:6-HYDROXY-7,8-DIHYDRO PURINE NUCLEOSIDE'>HPR</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Adenosine_deaminase Adenosine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.4 3.5.4.4]
|GENE=
}}
 
'''ATOMIC STRUCTURE OF ADENOSINE DEAMINASE COMPLEXED WITH A TRANSITION-STATE ANALOG: UNDERSTANDING CATALYSIS AND IMMUNODEFICIENCY MUTATIONS'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2ADA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=HPR:'>HPR</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 1ADA. Active as [http://en.wikipedia.org/wiki/Adenosine_deaminase Adenosine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.4 3.5.4.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ADA OCA].  
2ADA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry 1ADA. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ADA OCA].  


==Reference==
==Reference==
Atomic structure of adenosine deaminase complexed with a transition-state analog: understanding catalysis and immunodeficiency mutations., Wilson DK, Rudolph FB, Quiocho FA, Science. 1991 May 31;252(5010):1278-84. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=1925539 1925539]
Atomic structure of adenosine deaminase complexed with a transition-state analog: understanding catalysis and immunodeficiency mutations., Wilson DK, Rudolph FB, Quiocho FA, Science. 1991 May 31;252(5010):1278-84. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1925539 1925539]
[[Category: Adenosine deaminase]]
[[Category: Adenosine deaminase]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: hydrolase (amino)]]
[[Category: hydrolase (amino)]]


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