2ae2: Difference between revisions

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[[Image:2ae2.jpg|left|200px]]<br /><applet load="2ae2" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ae2.jpg|left|200px]]
caption="2ae2, resolution 1.90&Aring;" />
 
'''TROPINONE REDUCTASE-II COMPLEXED WITH NADP+ AND PSEUDOTROPINE'''<br />
{{Structure
|PDB= 2ae2 |SIZE=350|CAPTION= <scene name='initialview01'>2ae2</scene>, resolution 1.90&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene> and <scene name='pdbligand=PTO:PSEUDOTROPINE'>PTO</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Tropinone_reductase_II Tropinone reductase II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.236 1.1.1.236]
|GENE=
}}
 
'''TROPINONE REDUCTASE-II COMPLEXED WITH NADP+ AND PSEUDOTROPINE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2AE2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Datura_stramonium Datura stramonium] with <scene name='pdbligand=NAP:'>NAP</scene> and <scene name='pdbligand=PTO:'>PTO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Tropinone_reductase_II Tropinone reductase II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.236 1.1.1.236] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AE2 OCA].  
2AE2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Datura_stramonium Datura stramonium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AE2 OCA].  


==Reference==
==Reference==
Structure of tropinone reductase-II complexed with NADP+ and pseudotropine at 1.9 A resolution: implication for stereospecific substrate binding and catalysis., Yamashita A, Kato H, Wakatsuki S, Tomizaki T, Nakatsu T, Nakajima K, Hashimoto T, Yamada Y, Oda J, Biochemistry. 1999 Jun 15;38(24):7630-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10387002 10387002]
Structure of tropinone reductase-II complexed with NADP+ and pseudotropine at 1.9 A resolution: implication for stereospecific substrate binding and catalysis., Yamashita A, Kato H, Wakatsuki S, Tomizaki T, Nakatsu T, Nakajima K, Hashimoto T, Yamada Y, Oda J, Biochemistry. 1999 Jun 15;38(24):7630-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10387002 10387002]
[[Category: Datura stramonium]]
[[Category: Datura stramonium]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: tropane alkaloid biosynthesis]]
[[Category: tropane alkaloid biosynthesis]]


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