2ahx: Difference between revisions

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[[Image:2ahx.gif|left|200px]]<br /><applet load="2ahx" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ahx.gif|left|200px]]
caption="2ahx, resolution 2.396&Aring;" />
 
'''Crystal structure of ErbB4/HER4 extracellular domain'''<br />
{{Structure
|PDB= 2ahx |SIZE=350|CAPTION= <scene name='initialview01'>2ahx</scene>, resolution 2.396&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=YT3:YTTRIUM (III) ION'>YT3</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2]
|GENE= ERBB4, HER4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of ErbB4/HER4 extracellular domain'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2AHX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=NDG:'>NDG</scene>, <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=YT3:'>YT3</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AHX OCA].  
2AHX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AHX OCA].  


==Reference==
==Reference==
The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand., Bouyain S, Longo PA, Li S, Ferguson KM, Leahy DJ, Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15024-9. Epub 2005 Oct 3. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16203964 16203964]
The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand., Bouyain S, Longo PA, Li S, Ferguson KM, Leahy DJ, Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15024-9. Epub 2005 Oct 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16203964 16203964]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: x-ray crystallography; neuregulins; heparin-binding]]
[[Category: x-ray crystallography; neuregulins; heparin-binding]]


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