4p2a: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4p2a]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P2A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P2A FirstGlance]. <br> | <table><tr><td colspan='2'>[[4p2a]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P2A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P2A FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fau|2fau]], [[3qdo|3qdo]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2fau|2fau]], [[3qdo|3qdo]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p2a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p2a RCSB], [http://www.ebi.ac.uk/pdbsum/4p2a PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p2a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4p2a RCSB], [http://www.ebi.ac.uk/pdbsum/4p2a PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/VP26A_MOUSE VP26A_MOUSE]] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). [[http://www.uniprot.org/uniprot/SNX27_RAT SNX27_RAT]] Involved in endocytic trafficking (By similarity). In T lymphocytes, participates in endocytic recycling pathway. Recruits PSCDBP and HT4R to early endosomes (By similarity). | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Clairfeuille, T | [[Category: Clairfeuille, T]] | ||
[[Category: Collins, B | [[Category: Collins, B]] | ||
[[Category: Cullen, P | [[Category: Cullen, P]] | ||
[[Category: Gallon, M | [[Category: Gallon, M]] | ||
[[Category: Ghai, R | [[Category: Ghai, R]] | ||
[[Category: Mas, C | [[Category: Mas, C]] | ||
[[Category: Teasdale, R | [[Category: Teasdale, R]] | ||
[[Category: Retromer]] | [[Category: Retromer]] | ||
[[Category: Sorting nexin]] | [[Category: Sorting nexin]] | ||
[[Category: Transport protein]] | [[Category: Transport protein]] | ||
