2anw: Difference between revisions

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[[Image:2anw.gif|left|200px]]<br /><applet load="2anw" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2anw.gif|left|200px]]
caption="2anw, resolution 1.85&Aring;" />
 
'''Expression, crystallization and three-dimensional structure of the catalytic domain of human plasma kallikrein: Implications for structure-based design of protease inhibitors'''<br />
{{Structure
|PDB= 2anw |SIZE=350|CAPTION= <scene name='initialview01'>2anw</scene>, resolution 1.85&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=BAM:BENZAMIDINE'>BAM</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Plasma_kallikrein Plasma kallikrein], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.34 3.4.21.34]
|GENE= KLKB1, KLK3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Expression, crystallization and three-dimensional structure of the catalytic domain of human plasma kallikrein: Implications for structure-based design of protease inhibitors'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2ANW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=BAM:'>BAM</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Plasma_kallikrein Plasma kallikrein], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.34 3.4.21.34] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ANW OCA].  
2ANW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ANW OCA].  


==Reference==
==Reference==
Expression, crystallization, and three-dimensional structure of the catalytic domain of human plasma kallikrein., Tang J, Yu CL, Williams SR, Springman E, Jeffery D, Sprengeler PA, Estevez A, Sampang J, Shrader W, Spencer J, Young W, McGrath M, Katz BA, J Biol Chem. 2005 Dec 9;280(49):41077-89. Epub 2005 Sep 30. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16199530 16199530]
Expression, crystallization, and three-dimensional structure of the catalytic domain of human plasma kallikrein., Tang J, Yu CL, Williams SR, Springman E, Jeffery D, Sprengeler PA, Estevez A, Sampang J, Shrader W, Spencer J, Young W, McGrath M, Katz BA, J Biol Chem. 2005 Dec 9;280(49):41077-89. Epub 2005 Sep 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16199530 16199530]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Plasma kallikrein]]
[[Category: Plasma kallikrein]]
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[[Category: trypsin-like serine protease; enzymatically deglycosylated]]
[[Category: trypsin-like serine protease; enzymatically deglycosylated]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:29:12 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:51:50 2008''