4wqn: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wqn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wqn RCSB], [http://www.ebi.ac.uk/pdbsum/4wqn PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wqn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wqn RCSB], [http://www.ebi.ac.uk/pdbsum/4wqn PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/YTHD2_HUMAN YTHD2_HUMAN]] Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization of to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation.<ref>PMID:22575960</ref> <ref>PMID:24284625</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 02:33, 25 December 2014
Crystal structure of N6-methyladenosine RNA reader YTHDF2
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